Hormones: They control the human circadian rhythm, cause happiness after physical exercise, cause butterflies in one’s stomach and contribute to the chemistry of love, turn a pregnant woman’s life upside down and influence the growth of the fetus, in short, they are essential in the human individual development and homeostasis of organs. Hormones are mainly produced in the brain, pancreas, thyroid, kidney and the genital organs and represent the most important chemical messengers in the human organism. Hormone-dependent pathologic conditions are manifold and dysregulations need to be treated in order to warrant a healthy human body. Idiopathic short stature of children can e. g. be treated with growth hormones and researchers analyze the impact of hormone replacement therapy on well-being and health in the elderly [1, 2]. Hormones even enable the treatment of gender dysphoria, relieving the immense mental burden of the affected individuals [3]. In order to understand the complex functions of hormones, nowadays a lot of research is being conducted. This review will give a short overview of the latest reports published in Acta Physiologica about the research on the regulation of hormones and recently identified ways of how hormones modulate the human metabolism. This article is protected by copyright. All rights reserved.