Calcium Intake and Bone Mineral Density

I have discussed this the risks of calcium supplements previously, and now we find out that they do not do much good anyway. See my posts of 22nd July, 2015(calcium Doctors slam calcium and Vitamin D conflict of interest) and June 14th 2013 (calcium -Calcium confusion: scientists divided over supplements), Jan 12 2012 (calcium Link between calcium supplements and heart disease raises the question: Take them or toss them?) and other posts.

Calcium Intake and Bone Mineral Density

Dietary sources vs supplements

October 13, 2015

An increase in calcium intake either from dietary sources or from calcium supplements produced only small, non-progressive increases in bone mineral density (BMD) which is unlikely to translate into clinically significant reductions in fractures, according to a meta-analysis of 59 randomized controlled trials in participants aged 50 years and older. The study found:

• Increasing calcium intake from dietary sources increased BMD by 0.6% to 1.0% at the total hip and total body at 1 year and by 0.7% to 1.8% at these sites and the lumbar spine and femoral neck at 2 years.

• Calcium supplements increased BMD by 0.7% to 1.8% at all 5 skeletal sites at 1, 2, and over 2½ years, but the size of the increase in BMD at later time points was similar to the increase at 1 year.

• Increases in BMD were similar in trials of dietary sources of calcium and calcium supplements, in trials of calcium monotherapy vs co-administered calcium and vitamin D, in trials with calcium doses of ≥1000 mg/day vs <1000 mg/day, and ≤500 mg/day vs >500 mg/day.

Citation: Tai V, Leung W, Grey A, Reid IR, Bolland MJ. Calcium intake and bone mineral density: systematic review and meta-analysis. BMJ 2015;351:h4183. doi:10.1136/bmj.h4183.

Commentary: This meta-analysis of 59 randomized controlled trials of both dietary and supplemental calcium strongly suggests that the standard advice of increasing calcium intake is likely to yield little to any benefit on either BMD or risk of fracture in post-menopausal women. This low likelihood of benefit must be viewed in the context of reported increase in cardiovascular risk and the increased risk of kidney stones associated with increased calcium intake.1,2,3 This is another example of an intervention that intuitively makes complete sense which turns out not to be so after careful examination under the scrutiny of randomized trials. —Neil Skolnik, MD

1. Bolland MJ, Barber PA, Doughty RN, et al. Vascular events in healthy older women receiving calcium supplementation: randomised controlled trial. BMJ 2008;336:262-266.

2. Bolland MJ, Avenell A, Baron JA, et al. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ 2010;341:c3691.

3. Jackson RD, LaCroix AZ, Gass M, et al. Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med 2006;354:669-683.

About Dr Colin Holloway

Gp interested in natural hormone treatment for men and women of all ages

Posted on August 12, 2016, in Uncategorized. Bookmark the permalink. 3 Comments.

  1. Cannot help you with this one

  2. Colin, thank you for this article. This is a pertinent topic as always for me due to a MPA. I’ve not eaten dairy products now for 4 years. I am always amazed at the apparent lack of understanding in these studies of cofactors. The calcium is deposited in the bone with vitamin K2 and the all mighty powerful Magnesium. Vitamin A and boron are also important. The Vitamin D is a foregone conclusion. Even in Australia, the land of sunshine most people need D3 supplements, especially between April and October. I believe you have touched on the Magnesium side of the equation yourself in past posts. Any Doctor prescribing calcium supplements for bone health minus the cofactors is leading a patient down a dangerous slope to the aforementioned heart disease. Calcium needs to be ‘directed’ into our teeth and bones. The above all make that happen. It is wonderful to see question marks placed over gratuitous calcium supplementation. I’d love to see some posts on the cofactors. Thank you for your ongoing curiosity and benevolence towards the health of Australians. I open your emails before any others. Anna in Perth.

  3. Hi Dr Holloway

    I find your emails very interesting.

    Have you ever sent an email with information on kidney pain? I have for some time now woken in the morning with a VERY sore lower back and especially if I have slept for a long period (eg 8+hrs) but once I’m up it goes and it doesn’t hurt at all during the day. It is especially bad if I haven’t had approx 2L of water the day before. I’ve noticed on the internet many other women experience the same thing but I’m yet to see what the real cause or cure is?


    Sent from my iPhone

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