Early menopause as a cause of Chronic Fatigue Syndrome

I have known for a long time now that Chronic Fatigue Syndrome can be due to  hormonal imbalance, particularly the menopause.
Menopause:
doi: 10.1097/GME.0000000000000411
Original Articles

Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women

Boneva, Roumiana S. MD, PhD; Lin, Jin-Mann S. PhD; Unger, Elizabeth R. PhD, MD

 Abstract

Objective: This study aims to examine whether gynecologic conditions are associated with chronic fatigue syndrome (CFS).

Methods: This study includes a subset of 157 women from a population-based case-control study in Georgia, United States, conducted in 2004-2009. Gynecologic history was collected using a self-administered questionnaire. Crude odds ratios (ORs) with 95% CIs and ORs adjusted for body mass index and other covariates, where relevant, were estimated for gynecologic conditions between 84 CFS cases and 73 healthy controls.

Results: Cases and controls were of similar age. Women with CFS reported significantly more gynecologic conditions and surgical operations than controls: menopause status (61.9% vs 37.0%; OR, 2.37; 95% CI, 1.21-4.66), earlier mean age at menopause onset (37.6 vs 48.6 y; adjusted OR, 1.22; 95% CI, 1.09-1.36), excessive menstrual bleeding (73.8% vs 42.5%; adjusted OR, 3.33; 95% CI, 1.66-6.70), bleeding between periods (48.8% vs 23.3%; adjusted OR, 3.31; 95% CI, 1.60-6.86), endometriosis (29.8% vs 12.3%; adjusted OR, 3.67; 95% CI, 1.53-8.84), use of noncontraceptive hormonal preparations (57.1% vs 26.0%; adjusted OR, 2.95; 95% CI, 1.36-6.38), nonmenstrual pelvic pain (26.2% vs 2.7%; adjusted OR, 11.98; 95% CI, 2.57-55.81), and gynecologic surgical operation (65.5% vs 31.5%; adjusted OR, 3.33; 95% CI, 1.66-6.67), especially hysterectomy (54.8% vs 19.2%; adjusted OR, 3.23; 95% CI, 1.46-7.17). Hysterectomy and oophorectomy occurred at a significantly younger mean age in the CFS group than in controls and occurred before CFS onset in 71% of women with records of date of surgical operation and date of CFS onset.

Conclusions: Menstrual abnormalities, endometriosis, pelvic pain, hysterectomy, and early/surgical menopause are all associated with CFS. Clinicians should be aware of the association between common gynecologic problems and CFS in women. Further work is warranted to determine whether these conditions contribute to the development and/or perpetuation of CFS in some women.

About Dr Colin Holloway

Gp interested in natural hormone treatment for men and women of all ages

Posted on October 19, 2015, in Uncategorized. Bookmark the permalink. 2 Comments.

  1. Having had a hysterectomy at 45 and a long sufferer of endometritiousis , I agree that I have also been a person that has had CFS . I can sleep 2hrs inthe afternoon and still need my 8hrs at night. Dr Holloways Hrt has helped. Cheryl Hayes .

  2. Hi Dr Holloway – I went through menopause early at the age of 47 and have chronic fatigue. What can I do or take to help with it.

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